Medical treatment for Crohns disease and ulcerative colitis has two main goals: achieving remission (the absence of flagyl for ulcerative colitis symptoms) and, once that is accomplished, maintaining remission (prevention of flare-ups). To accomplish these goals, treatment is aimed at controlling the ongoing inflammation in the intestinethe cause of IBD symptoms. Antibiotics are frequently used as a primary treatment approach in IBD, even though no specific infectious agent where can i get flagyl over the counter has been identified as the cause of these illnesses. However, researchers believe that antibiotics can flagyl antibiotic side effects help control symptoms of IBD by flagyl for ulcerative colitis reducing intestinal bacteria and by directly suppressing the intestine's immune system. Antibiotics are effective as long-term therapy in some people with IBD, particularly Crohn's disease patients who have fistulas (abnormal channels between two loops of intestine, flagyl is used to treat what infections or between the intestine and another structuresuch as the skin) or recurrent abscesses (pockets of pus) near their anus. Patients whose active disease is successfully treated with antibiotics may be kept on these as maintenance therapy as long as the medications remain effective. Although helpful in people with Crohn's disease, antibiotics generally are not considered useful for those with ulcerative colitis, either for maintaining remission or in acute situations. Clinical trials have not shown that antibiotics have value in treating severe ulcerative colitis. The exception is toxic megacolon, a condition that places people at high risk for perforation. This life-threatening complication is characterized by a distended abdomen and an extremely inflated colon. Oral Medications, although there are several antibiotics that may be effective for certain people, the two most commonly prescribed in IBD are: Metronidazole (Flagyl ciprofloxacin (Cipro both metronidazole and ciprofloxacin are broad-spectrum antibiotics that by definition fight a wide range of bacteria. Metronidazole is the most extensively studied antibiotic flagyl for ulcerative colitis in IBD. As a primary therapy for active Crohn's, this drug has been shown to be superior to placebo (sugar pill) and equal to sulfasalazineespecially when the illness affects the colon. Metronidazole also has been shown to reduce the recurrence of Crohn's for the first three months after ileum resection surgery. In more than 50 percent of those treated, metronidazole can be effective in managing perineal Crohn's (disease involving the pelvic area). Metronidazole also is used to suppress an overgrowth. Difficile, a type of bacteria that causes inflammation. Another indication for metronidazole is in people who develop "pouchitis" after ileal-pouch anal anastomosis surgery. In this procedure, after the colon is removed, an internal pouch is formed from the patient's ileum (the lowest part of the small intestine)averting the need for an external appliance. Sometimes the pouch becomes severely inflamed; hence the term "pouchitis.". Ciprofloxacin is commonly used to treat active Crohn's disease and pouchitis. It is also far safer than metronidazole. Alternative Methods of Delivery, both metronidazole and ciprofloxacin are available in intravenous (IV) forms and may be used as such when needed. Side Effects, metronidazole: Common side flagyl for ulcerative colitis effects may include nausea, vomiting, loss of appetite, a metallic taste, diarrhea, dizziness, headaches, and discolored urine (dark or reddish brown). Another side effect of long-term use is tingling of the hands and feet, which may persist even after the drug is discontinued. If you develop such tingling, notify your doctor immediately. The medication should flagyl and depression be stopped and not restarted. Ciprofloxacin: Side effects may include headaches, nausea, vomiting, diarrhea, abdominal pain, rash, and restlessness, all of which are rare. People taking several different medicines, whether prescription or over-the-counter, should always be on the lookout for interactions between drugs. Drug interactions may decrease a medication's effectiveness, intensify the action of a drug, or cause unexpected side effects. Before taking any medication, read the label carefully. Be sure to tell your doctor about all the drugs you're taking (even over-the-counter medications or complementary therapies) and any medical condition you may have. Special Considerations, metronidazole affects the breakdown of alcohol, flagyl for ulcerative colitis which may result in nausea and vomiting. Therefore, avoid alcohol in any form while on this medication and until at least two days following the last dose. Ciprofloxacin can interact with antacids flagyl for ulcerative colitis (such as Rolaids and Tums so do not take both within the same few hours. It also interacts similarly with vitamin and mineral supplements that contain calcium, iron, or zinc.
Flagyl or metronidazole
Contraindications, hypersensitivity to metronidazole or other nitroimidazoles (although cautious desensitization has been applied). Pregnancy, 1st trimester (controversial use of disulfiram within past 2 weeks; use of alcohol during therapy or within 3 days of discontinuing therapy. Cautions, encephalopathcy, seizures, aseptic meningitis, and neuropathies reported with increase in dose and chronic therapy. Superinfection may occur with prolonged use. Severe hepatic impairment; administer lower doses with caution. Use with caution; potential accumulation in end stage renal disease; supplemental doses may be needed in patients receiving hemodialysis. Use with caution in history of heart failure, hepatic failure,. Pylori infection, renal impairment. Use with care in patients with evidence of or history of blood dyscrasia; agranulocytosis, leukopenia and neutropenia have been associated with metronidazole administration; monitor complete blood count; monitor complete blood count (CBC) for leukopenia before, during, and after prolonged repeated therapy. Avoid alcohol while taking medication and for at least 1 day after discontinuation. Antiandrogen: May cause gynecomastia, known or previously unrecognized candidiasis may present more prominent symptoms during therapy and requires treatment with a candicidal agent. Metronidazole injection, USP contains 790 mg of sodium per 100 mL; use care when administering injection to patients receiving a controlled sodium diet or corticosteroids or to patients predisposed to edema. Severe neurological disturbances, including encephalopathy, cerebellar symptoms, convulsive seizures, peripheral neuropathy, optic neuropathy, and aseptic meningitis, reported in patients treated with metronidazole; advise patients to report neurologic symptoms that occur during metronidazole administration; discontinue metronidazole treatment if any abnormal neurologic symptoms occur such as ataxia. Cases flagyl or metronidazole of severe hepatotoxicity/acute hepatic failure, including cases with a fatal outcome with very rapid onset after treatment initiation in patients with Cockayne syndrome reported with products containing metronidazole for systemic use; in this population, metronidazole should therefore be used after careful benefit-risk assessment and. Drug interaction overview, metronidazole reported to potentiate anticoagulant effect of warfarin and other oral coumarin anticoagulants, resulting in a prolongation of prothrombin time and increased risk of hemorrhages; prothrombin time and international normalized ratio (INR) should be carefully monitored and anticoagulant dose adjusted accordingly; monitor. Metronidazole reported to increase plasma flagyl or metronidazole concentrations of busulfan, which can result in an increased risk for serious busulfan toxicity such as sinusoidal obstruction syndrome, gastrointestinal mucositis, and hepatic veno-occlusive disease; metronidazole should not be administered concomitantly with busulfan unless benefit outweighs risk. Simultaneous administration of drugs that decrease microsomal liver enzyme activity, such as cimetidine, may decrease metabolism and reduce plasma clearance of metronidazole which may result in metronidazole toxicity. Simultaneous administration of drugs that induce microsomal liver enzyme activity, such as phenytoin or phenobarbital, may accelerate elimination of metronidazole and therefore decrease its efficacy. Concomitant use of metronidazole and CYP3A4 substrates (e.g., amiodarone, flagyl or metronidazole tacrolimus, cyclosporine, carbamazepine, phenytoin, and quinidine) may increase respective CYP3A4-substrate plasma levels; monitoring of plasma concentrations of CYP3A4 substrates may be necessary. Metronidazole decreases clearance of 5-fluorouracil and may therefore cause 5-fluorouracil toxicity. Metronidazole may potentiate effects of vecuronium. Generic name: Metronidazole, other brand name: Protostat, what Flagyl. Flagyl (metronidazole) is an antibacterial drug that is classified as a broad-spectrum antibiotic. It is used to kill any bacteria in the body that are causing infection. In some cases, Flagyl may be used to treat infections or other complications of IBD. It might be given alternately or at the same time as ciprofloxacin, another type of antibiotic. How Flagyl Is Taken, when taken at home to treat an infection, Flagyl is taken orally in tablet form. In order for Flagyl to effectively kill harmful bacteria, it is important to maintain a constant level of the drug in the blood. Therefore, it must be taken at regular intervals without missing any doses. Take Flagyl with 8 ounces of water. Flagyl can be taken by itself, or it can be taken with meals. If dry mouth becomes bothersome, try chewing gum, or sucking on hard candy or ice chips. Why Flagyl Is Prescribed, flagyl is used to fight off, or to prevent, a bacterial infection. It is used to treat a wide variety of infections, including those flagyl or metronidazole in the abdomen, bones, joints, nervous system, respiratory tract, and skin, as well as vaginal and intestinal infections. If A Dose Is Missed. When a dose is missed, take it as soon as it is remembered.
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